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Free radical scavenging capacity
of Brahmi on DNA damage

Department of Biochemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy, conducted a study to explain the free radical scavenging capacity of a methanol extract of Brahmi. The study also investigated the effect on DNA cleavage induced by H2O2 UV-photolysis.

In addition, the study examined whether this plant extract is capable of reducing the hydrogen peroxide-induced cytotoxicity and DNA damage in human non-immortalized fibroblasts. It showed a dose-dependent free radical scavenging capacity and a protective effect on DNA cleavage. These results were confirmed by a significant protective effect on H2O2-induced cytoxicity and DNA damage in human non-immortalized fibroblasts.

The antioxidant capacity of Brahmi may explain, at least in part, the reported antistress, immunomodulatory, cognition-facilitating, antiinflammatory and antiaging effects produced by it in experimental animals and in clinical situations and may justify further investigation of its other beneficial properties.

Moreover, this experimental evidence suggests that because of its antioxidant activity, this Ayurvedic drug may be useful in the treatment of human pathologies in which free radical production plays a key role.

Brahmi extract reduces morphine-
induced withdrawal symptoms


Effect of Brahmi on nitric oxide-related toxicity

Evaluation of antistress effect of Brahmi

In vitro effect of Brahmi on anti-Helicobacter pylori activity

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